New vaccine side effect? In Israel, six people
develop herpes zoster
HZ is characterized by a small, red rash that develops on the
skin and itches. If complications develop, it can cause nerve
damage and pain, including a prolonged burning session on
the skin.
By MAAYAN JAFFE-HOFFMAN
APRIL 19, 2021 19:46

A rash from herpes zoster [Illustrative].
(photo credit: Wikimedia Commons)
A new study published this month by researchers from Tel Aviv Sourasky Medical Center and
Carmel Medical Center in Haifa found that the risk of developing herpes zoster (HZ) infection
following a coronavirus vaccination in people with autoimmune inflammatory rheumatic diseases
(AIIRD) increases.
“We cannot say the vaccine is the cause at this point,” lead researcher Dr. Victoria Furer of the
hospital’s Department of Rheumatology told The Jerusalem Post. “We can say it might be a trigger
in some patients.”
HZ is characterized by a small, red rash that develops on the skin and itches. If complications
develop, it can cause nerve damage and pain, including a prolonged burning session on the skin
even after it goes away.
The study was carried out on 491 patients with AIIRD and 99 controls at the hospitals. Of the 491
patients, 1.2% or six people developed HZ. Five of them got the herpes infection after the first dose
and one after the second.
Furer said that five of the six patients who developed HZ were young, had mild cases of
autoimmune disease and were taking little if any medications for it, which means they should not
have been at increased risk for developing HZ.
“That is why we reported on it,” she said.
HZ tends to develop more in people over the age of 50.

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